Abstract
We have previously reported on phase I/II studies of irinotecan plus S-1 therapy for advanced gastric cancer. Based on the safety and efficacy data that were obtained, this phase II study was planned to assess the efficacy of irinotecan plus S-1 for patients with advanced colorectral cancer. A total of 40 patients are enrolled at 13 medical institutions. The objective of this study was to establish a useful chemotherapy regimen for an out-patient setting.
Publication types
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Clinical Trial
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Clinical Trial, Phase II
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Multicenter Study
MeSH terms
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Adenocarcinoma / drug therapy*
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Administration, Oral
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Adolescent
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Adult
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Aged
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Ambulatory Care*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Camptothecin / administration & dosage
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Camptothecin / analogs & derivatives*
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Colorectal Neoplasms / drug therapy*
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Drug Administration Schedule
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Drug Combinations
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Humans
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Irinotecan
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Middle Aged
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Oxonic Acid / administration & dosage
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Pyridines / administration & dosage
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Tegafur / administration & dosage
Substances
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Drug Combinations
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Pyridines
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S 1 (combination)
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Tegafur
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Oxonic Acid
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Irinotecan
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Camptothecin