Design, synthesis and antimalarial activity of trifluoromethylartemisinin-mefloquine dual molecules

Chembiochem. 2005 Apr;6(4):648-52. doi: 10.1002/cbic.200400347.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antimalarials / chemical synthesis*
  • Antimalarials / pharmacology
  • Antimalarials / therapeutic use
  • Artemisinins / chemistry*
  • Drug Design*
  • Hydrocarbons, Halogenated / chemistry*
  • Malaria / drug therapy
  • Mefloquine / analogs & derivatives*
  • Mefloquine / chemistry
  • Mice
  • Molecular Structure
  • Parasitemia / drug therapy
  • Plasmodium berghei / drug effects
  • Plasmodium falciparum / drug effects

Substances

  • Antimalarials
  • Artemisinins
  • Hydrocarbons, Halogenated
  • Mefloquine