Laryngospasm: an underdiagnosed symptom of X-linked spinobulbar muscular atrophy

Neurology. 2005 Feb 22;64(4):753-4. doi: 10.1212/01.WNL.0000151978.74467.E7.

Abstract

The authors reviewed the occurrence and concomitant factors of laryngospasm in X-linked spinobulbar muscular atrophy (Kennedy disease [KD]). Recurrent laryngospasm was observed in 47% of 49 patients with KD, but in only 2% of a control group of patients with early-stage ALS.

MeSH terms

  • Gastroesophageal Reflux / complications
  • Gastroesophageal Reflux / diagnosis
  • Gastroesophageal Reflux / drug therapy
  • Genetic Diseases, X-Linked / complications*
  • Genetic Diseases, X-Linked / diagnosis
  • Humans
  • Laryngismus / diagnosis
  • Laryngismus / etiology*
  • Laryngismus / prevention & control
  • Male
  • Middle Aged
  • Muscular Disorders, Atrophic / complications*
  • Muscular Disorders, Atrophic / diagnosis
  • Muscular Disorders, Atrophic / genetics
  • Receptors, Androgen / deficiency
  • Receptors, Androgen / genetics
  • Respiratory Sounds / etiology
  • Risk Factors
  • Sleep Disorders, Intrinsic / complications

Substances

  • AR protein, human
  • Receptors, Androgen