Primary lumbosacral Wilms tumor associated with diastematomyelia and occult spinal dysraphism. A report of a rare case and a short review of literature

Childs Nerv Syst. 2005 Mar;21(3):240-3. doi: 10.1007/s00381-004-0989-0. Epub 2004 Nov 20.

Abstract

Background: The occurrence of an extrarenal Wilms tumor in the lumbosacral region is an extremely uncommon condition.

Case report: We report a case of Wilms tumor in the lumbosacral region that was associated with diastematomyelia and occult spina bifida. An 18-month-old girl presented with a swelling over the lower back with a tuft of hair on it, which she had had since birth. Imaging of the spine revealed spina bifida, bony diastematomyelia, and tethered cord. Excision of the bony spur and detethering of the cord was done. After a year, she had recurrence of swelling at the same site, weakness of both lower limbs, and incontinence of bladder and bowel. Excision of the mass and bony spur and detethering of the spinal cord were done. Histopathological examination showed features of a Wilms tumor.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Immunohistochemistry / methods
  • Infant
  • Keratins / metabolism
  • Kidney Neoplasms / complications*
  • Kidney Neoplasms / metabolism
  • Kidney Neoplasms / pathology
  • Lumbosacral Region / pathology
  • Magnetic Resonance Imaging / methods
  • Spina Bifida Occulta / complications*
  • Spina Bifida Occulta / metabolism
  • Spina Bifida Occulta / pathology
  • Spinal Cord Neoplasms / complications*
  • Spinal Cord Neoplasms / metabolism
  • Spinal Cord Neoplasms / pathology
  • Spinal Dysraphism / complications*
  • Spinal Dysraphism / metabolism
  • Spinal Dysraphism / pathology
  • Staining and Labeling
  • Wilms Tumor / complications*
  • Wilms Tumor / metabolism
  • Wilms Tumor / pathology

Substances

  • Keratins