Abstract
A lignan and two acylphloroglucinols have been isolated from the ethyl acetate soluble fraction of the whole plant of Indigofera hetrantha. Their structures have been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. Compounds 1-3 displayed promising inhibitory potential against enzyme lipoxygenase in concentration-dependent manner.
MeSH terms
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Disaccharides / chemistry*
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Disaccharides / isolation & purification
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Disaccharides / pharmacology
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Indigofera / chemistry*
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Lipoxygenase Inhibitors / chemistry*
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Lipoxygenase Inhibitors / isolation & purification*
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Lipoxygenase Inhibitors / pharmacology
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Magnetic Resonance Spectroscopy
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Monosaccharides / chemistry*
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Monosaccharides / isolation & purification
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Monosaccharides / pharmacology
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Naphthalenes / chemistry*
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Naphthalenes / isolation & purification
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Naphthalenes / pharmacology
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Phloroglucinol / analogs & derivatives*
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Phloroglucinol / chemistry*
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Phloroglucinol / isolation & purification
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Phloroglucinol / pharmacology
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Plants, Medicinal / chemistry
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
Substances
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1-((3-methylbutanoyl)phloroglucinyl)-beta-D-glucopyranoside
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1-((pentanoyl)phloroglucinyl)-beta-D-glucopyranoside
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Disaccharides
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Lipoxygenase Inhibitors
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Monosaccharides
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Naphthalenes
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lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside
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Phloroglucinol