Abstract
Reported is the association of REM behavior disorder (RBD) with late-onset, sleep-related, tonic-clonic seizures in two elderly men. In each patient, RBD preceded the onset of seizures by several years. The authors hypothesize that REM sleep disruption may facilitate seizure occurrence.
MeSH terms
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Aged
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Anticonvulsants / therapeutic use
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Brain / physiopathology*
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Clonazepam / therapeutic use
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Electroencephalography
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Epilepsy / complications*
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Epilepsy / drug therapy
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Epilepsy / physiopathology*
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Humans
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Male
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Middle Aged
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Polysomnography
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REM Sleep Behavior Disorder / complications*
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REM Sleep Behavior Disorder / drug therapy
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REM Sleep Behavior Disorder / physiopathology*
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Seizures / complications
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Seizures / physiopathology
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Sleep Apnea, Central / complications
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Sleep Apnea, Central / drug therapy
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Sleep Apnea, Central / physiopathology
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Sleep, REM / physiology
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Treatment Outcome
Substances
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Anticonvulsants
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Clonazepam