Physical determinants of systolic murmur intensity in aortic stenosis

Am J Cardiol. 2005 Mar 15;95(6):774-6. doi: 10.1016/j.amjcard.2004.11.035.

Abstract

We investigated which physical parameter has the greatest impact on the perceived loudness of a systolic murmur in aortic stenosis. Loudness of murmur in aortic stenosis correlated best with peak momentum transfer--and thus with body size--so that loud murmurs predict severe disease less reliably in larger patients.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aorta / physiopathology
  • Aortic Valve Insufficiency / diagnosis
  • Aortic Valve Insufficiency / physiopathology
  • Aortic Valve Stenosis / diagnosis
  • Aortic Valve Stenosis / physiopathology*
  • Body Size*
  • Female
  • Heart Auscultation*
  • Heart Murmurs*
  • Hemodynamics / physiology
  • Humans
  • Male
  • Middle Aged
  • Muscle, Smooth, Vascular / physiopathology
  • Sound Spectrography
  • Systole / physiology*
  • Vibration