Evaluation of left ventricular dimensions and function in Marfan's syndrome without significant valvular regurgitation

Lilian J Meijboom; Janneke Timmermans; Johan P van Tintelen; Gijs J Nollen; Julie De Backer; Maarten P van den Berg; Gerard H Boers; Barbara J M Mulder

doi:10.1016/j.amjcard.2004.11.042

Evaluation of left ventricular dimensions and function in Marfan's syndrome without significant valvular regurgitation

Am J Cardiol. 2005 Mar 15;95(6):795-7. doi: 10.1016/j.amjcard.2004.11.042.

Authors

Lilian J Meijboom¹, Janneke Timmermans, Johan P van Tintelen, Gijs J Nollen, Julie De Backer, Maarten P van den Berg, Gerard H Boers, Barbara J M Mulder

Affiliation

¹ Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.

PMID: 15757617
DOI: 10.1016/j.amjcard.2004.11.042

Abstract

Left ventricular dimensions and systolic function were studied using echocardiography in 234 patients with Marfan's syndrome without significant valvular regurgitation. Left ventricular dimensions and systolic function were found to be normal in most patients with Marfan's syndrome. Some involvement of the left ventricle may have been present in a small group of these patients. No patients, however, fulfilled the criteria for dilated cardiomyopathy.

MeSH terms

Adolescent
Adrenergic beta-Antagonists / therapeutic use
Adult
Aged
Aortic Valve Insufficiency / diagnosis
Aortic Valve Insufficiency / physiopathology
Cardiac Volume / drug effects
Cardiac Volume / physiology*
Cardiomyopathy, Dilated / diagnosis
Cardiomyopathy, Dilated / physiopathology
Echocardiography / drug effects
Female
Follow-Up Studies
Humans
Male
Marfan Syndrome / diagnosis
Marfan Syndrome / drug therapy
Marfan Syndrome / physiopathology*
Middle Aged
Mitral Valve Insufficiency / diagnosis
Mitral Valve Insufficiency / physiopathology
Myocardial Contraction / drug effects
Myocardial Contraction / physiology
Ventricular Function, Left / drug effects
Ventricular Function, Left / physiology*

Substances

Adrenergic beta-Antagonists