Body temperature - a marker of infarct size in the era of early reperfusion

Cardiology. 2005;103(4):169-73. doi: 10.1159/000084589. Epub 2005 Mar 21.

Abstract

We measured body temperature in 40 consecutive patients treated for a first ST elevation acute myocardial infarction (AMI) with primary percutaneous coronary interventions. Left ventricular function was assessed by echocardiography, and blood samples were drawn for highly sensitive C-reactive protein (hs-CRP), white blood cell (WBC) count, fibrinogen, creatine kinase (CK), and cardiac troponin I levels (cTnI). The median (25th, 75th quartiles) peak 24-hour temperature was 37.4 degrees C (36.9 degrees C, 37.6 degrees C). Variables significantly associated with peak 24-hour temperature were CK (p = 0.01, r = 0.42), wall motion index (p = 0.01, r = 0.41), hs-CRP (p = 0.01, r = 0.41), and cTnI (p = 0.03, r = 0.35). There was no significant correlation between peak 24-hour temperature and WBC count (p = 0.39, r = 0.14) and fibrinogen (p = 0.12, r = 0.21). Thus, peak 24-hour body temperature after ST elevation AMI probably reflects infarct size rather than a nonspecific inflammatory response.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / blood
  • Body Temperature / physiology*
  • C-Reactive Protein / analysis
  • Cohort Studies
  • Creatine Kinase / blood
  • Echocardiography
  • Female
  • Fever / physiopathology*
  • Fibrinogen / analysis
  • Follow-Up Studies
  • Humans
  • Image Processing, Computer-Assisted
  • Leukocyte Count
  • Male
  • Middle Aged
  • Myocardial Contraction / physiology
  • Myocardial Infarction / blood
  • Myocardial Infarction / pathology*
  • Myocardial Infarction / physiopathology
  • Myocardial Reperfusion*
  • Prospective Studies
  • Troponin I / blood
  • Ventricular Function, Left / physiology

Substances

  • Biomarkers
  • Troponin I
  • Fibrinogen
  • C-Reactive Protein
  • Creatine Kinase