Atrophic vaginitis is not only treatable but preventable. Because the vagina is an estrogen-dependent organ, the mainstay of management is estrogen replacement therapy, which should be initiated with the onset of ovarian decline at menopause or when a woman presents with symptoms of atrophic vaginitis. Lubricants and vaginal moisturizers may be useful adjuncts. Regular sexual activity is also helpful in maintaining a healthy, functional vagina.