Squalene aspiration pneumonia in children: radiographic and CT findings as the first clue to diagnosis

Pediatr Radiol. 2005 Jun;35(6):619-23. doi: 10.1007/s00247-005-1439-1. Epub 2005 Apr 2.

Abstract

Background: The diagnosis of squalene aspiration pneumonia in children is often difficult because of minimal non-specific symptoms.

Objective: To investigate the radiological findings of squalene aspiration pneumonia in children.

Materials and methods: We reviewed the chest radiographs (n = 8) and CT scans (n = 7), including high-resolution CT (n = 3), of eight patients (four boys, four girls; age 3 months to 6 years) with squalene aspiration pneumonia. All patients presented minimal symptoms.

Results: Chest radiographs showed right-sided predominantly parahilar infiltrations. The extent and the opacity of the lesions decreased slowly during the follow-up period (mean 5.4 months) after halting the exposure. On CT, affected areas appeared as dense consolidations surrounded by ground-glass opacities showing a crazy-paving pattern in a geographic lobular distribution in all patients. The lesions were predominantly in the right lung and dependent areas in all patients and extensively involved all pulmonary lobes in five patients.

Conclusions: These radiological findings, although non-specific, can lead to an appropriate diagnosis, particularly when patients present few symptoms.

MeSH terms

  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant
  • Male
  • Pneumonia, Lipid / diagnostic imaging*
  • Radiography, Thoracic
  • Retrospective Studies
  • Squalene / toxicity*
  • Tomography, X-Ray Computed*

Substances

  • Squalene