Abstract
Beta-Hexachlorocyclohexane (beta-HCH) is the most recalcitrant among the alpha-, beta-, gamma-, and delta-isomers of HCH and causes serious environmental pollution problems. We demonstrate here that the haloalkane dehalogenase LinB, reported earlier to mediate the second step in the degradation of gamma-HCH in Sphingomonas paucimobilis UT26, metabolizes beta-HCH to produce 2,3,4,5,6-pentachlorocyclohexanol.
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Biodegradation, Environmental
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Cyclohexanols / metabolism*
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Gene Expression Regulation, Bacterial
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Hexachlorocyclohexane / metabolism*
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Hydrolases / genetics
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Hydrolases / metabolism*
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Sphingomonas / enzymology*
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Sphingomonas / genetics
Substances
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2,3,4,5,6-pentachlorocyclohexanol
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Bacterial Proteins
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Cyclohexanols
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Hexachlorocyclohexane
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Hydrolases
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haloalkane dehalogenase
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beta-hexachlorocyclohexane