Retrospective serological investigation of severe acute respiratory syndrome coronavirus antibodies in recruits from mainland China

Clin Diagn Lab Immunol. 2005 Apr;12(4):552-4. doi: 10.1128/CDLI.12.4.552-554.2005.

Abstract

Different assays were used to analyze 1,621 serum specimens collected from military recruits from the People's Republic of China in 2002 for severe acute respiratory syndrome (SARS) coronavirus antibodies. The results demonstrated that the subjects either had rarely been exposed to the virus before the 2003 SARS outbreak or had not been exposed but the nucleocapsid protein cross-reacted with other antibodies in humans.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antibodies, Viral / blood*
  • China / epidemiology
  • Enzyme-Linked Immunosorbent Assay / methods
  • Fluorescent Antibody Technique, Indirect / methods
  • Humans
  • Male
  • Mass Screening
  • Neutralization Tests / methods
  • Retrospective Studies
  • Sensitivity and Specificity
  • Serologic Tests / methods
  • Severe Acute Respiratory Syndrome / blood*
  • Severe acute respiratory syndrome-related coronavirus / immunology*

Substances

  • Antibodies, Viral