Abstract
This study reported the changes in carotid intima-media thickness (IMT) during a 36-month period in 233 HIV-infected patients. Median IMT increased in the first 12 months and then decreased by month 36. The prevalence of treatment with lipid-lowering agents and protease inhibitor-free highly active antiretroviral therapy regimens increased, whereas smoking prevalence decreased. The progression of atherosclerosis in HIV-infected patients can be controlled. The impact of individual measures to reduce the cardiovascular risk should be evaluated further.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antiretroviral Therapy, Highly Active
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Arteriosclerosis / pathology
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Arteriosclerosis / therapy
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Arteriosclerosis / virology*
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Carotid Artery Diseases / pathology
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Carotid Artery Diseases / virology
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Carotid Artery, Common
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Cholesterol, HDL / blood
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Disease Progression
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Drug Therapy, Combination
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Female
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Follow-Up Studies
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France
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HIV Infections / complications*
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HIV Infections / pathology
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HIV Infections / therapy
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HIV-1*
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Humans
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Hypolipidemic Agents / therapeutic use
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Male
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Middle Aged
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Risk Factors
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Smoking
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Tunica Intima / pathology
Substances
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Cholesterol, HDL
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Hypolipidemic Agents