Abstract
We report the use of quantum dots (QDs) to identify the presence and monitor the progression of respiratory syncytial virus (RSV) infection over time by labeling the F and G proteins. In addition, co-localization of these viral proteins was shown using confocal microscopy. The implications of these results are that QDs may provide a method for early, rapid detection of viral infection and open the door for future studies of the intricate spatial features cell trafficking of viral proteins.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Cell Line
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Fluorescent Dyes*
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Humans
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Quantum Dots*
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Respiratory Syncytial Virus Infections / diagnosis*
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Respiratory Syncytial Virus, Human / physiology
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Viral Envelope Proteins / analysis*
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Viral Envelope Proteins / chemistry
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Viral Fusion Proteins / analysis*
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Viral Fusion Proteins / chemistry
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Virus Replication / physiology
Substances
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Fluorescent Dyes
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Viral Envelope Proteins
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Viral Fusion Proteins
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attachment protein G