Cure of post-traumatic recurrent multiresistant Gram-negative rod meningitis with intraventricular colistin

J Infect. 2005 May;50(4):348-52. doi: 10.1016/j.jinf.2004.05.008.

Abstract

A 28-year-old man developed five episodes of meningitis, all due to multiresistant Gram-negative rods during his 7-month hospitalisation after head trauma. This patient's recurrent meningitis was solved only when colistin and amikacin were given by the intraventricular in addition to the intravenous route for a long period of time, specifically 6 weeks.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Colistin / administration & dosage*
  • Craniocerebral Trauma / complications*
  • Drug Resistance, Multiple, Bacterial
  • Gram-Negative Bacterial Infections / drug therapy*
  • Gram-Negative Bacterial Infections / etiology
  • Humans
  • Injections, Intraventricular
  • Male
  • Meningitis, Bacterial / drug therapy*
  • Meningitis, Bacterial / etiology
  • Neurosurgical Procedures / adverse effects
  • Recurrence

Substances

  • Colistin