Zonisamide for absence seizures

Angus Wilfong; Rebecca Schultz

doi:10.1016/j.eplepsyres.2005.02.006

Zonisamide for absence seizures

Epilepsy Res. 2005 Mar-Apr;64(1-2):31-4. doi: 10.1016/j.eplepsyres.2005.02.006. Epub 2005 Apr 19.

Authors

Angus Wilfong¹, Rebecca Schultz

Affiliation

¹ Pediatric Neurology, Texas Children's Hospital, Baylor College of Medicine, 6621 Fannin, CC1710 Houston, TX 77030, USA. [email protected]

PMID: 15847848
DOI: 10.1016/j.eplepsyres.2005.02.006

Abstract

This chart review investigated the efficacy and safety of zonisamide in 45 patients aged < or = 18 years with absence seizures. Of these patients, 23 (51.1%) achieved freedom from absence seizures. Two patients discontinued zonisamide, 1 for increased seizures and 1 for sleepiness and inefficacy. These data support the efficacy of zonisamide in treating absence seizures.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't
Review

MeSH terms

Adolescent
Anticonvulsants / therapeutic use*
Body Weight / drug effects
Child
Child, Preschool
Clinical Trials as Topic
Epilepsy, Absence / drug therapy*
Female
Humans
Isoxazoles / therapeutic use*
Male
Treatment Outcome
Zonisamide

Substances

Anticonvulsants
Isoxazoles
Zonisamide