Prognostic value of median and tibial somatosensory evoked potentials in acute stroke

Neurosci Lett. 2005 May;380(1-2):99-104. doi: 10.1016/j.neulet.2005.01.023. Epub 2005 Feb 1.

Abstract

The predictive values of early somatosensory evoked potentials (SSEPs) for the functional outcome after stroke are investigated. Ninety-four stroke patients (mean age: 61.2, S.D.: 11.8) with CT confirmed diagnoses of middle cerebral artery (MCA) infarction in 71 and supratentorial intracerebral hemorrhage in 23. Median and tibial SSEPs were recorded within 3 days of onset. SSEP parameters were compared to motor (MRC) and functional ability (Barthel index) followed up at 1, 3, 6 and 12 months. Upper limb MRC remains the strongest single predictor of functional outcome, determining 54.3% of Barthel index value at 12 months. The highest predictive value among SSEP parameters has N20-P25 amplitude ratio-34.5%. Combined application of upper limb MRC and N20-P25 amplitude ratio provided significantly stronger prognostic information-66%. Combined assessment of SSEP parameters and muscle power in acute stroke considerably improves prediction of functional outcome.

Publication types

  • Comparative Study

MeSH terms

  • Activities of Daily Living
  • Aged
  • Aged, 80 and over
  • Evoked Potentials, Somatosensory / physiology*
  • Female
  • Follow-Up Studies
  • Functional Laterality / physiology
  • Humans
  • Male
  • Median Nerve / physiopathology*
  • Middle Aged
  • Motor Activity / physiology
  • Predictive Value of Tests
  • Prognosis
  • Prospective Studies
  • Reference Values
  • Stroke / classification
  • Stroke / physiopathology*
  • Tibial Nerve / physiopathology*
  • Time Factors
  • Tomography, X-Ray Computed / methods