Computed tomography versus bronchography in the diagnosis and management of tracheobronchomalacia in ventilator dependent infants

Arch Dis Child Fetal Neonatal Ed. 2005 Jul;90(4):F290-3. doi: 10.1136/adc.2004.062604. Epub 2005 Apr 27.

Abstract

Aim: To assess the relative accuracy of dynamic spiral computed tomography (CT) compared with tracheobronchography, in a population of ventilator dependent infants with suspected tracheobroncho-malacia (TBM).

Setting: Paediatric intensive care unit in a tertiary teaching hospital.

Patients and methods: Infants referred for investigation and management of ventilator dependence and suspected of having TBM were recruited into the study. Tracheobronchography and CT were performed during the same admission by different investigators who were blinded to the results of the other investigation. The study was approved by the hospital research ethics committee, and signed parental consent was obtained.

Results: Sixteen infants were recruited into the study. Fifteen had been born prematurely, and five had cardiovascular malformations. In 10 patients there was good or partial correlation between the two investigations, but in six patients there was poor or no correlation. Bronchography consistently showed more dynamic abnormalities, although CT picked up an unsuspected double aortic arch. Radiation doses were 0.27-2.47 mSv with bronchography and 0.86-10.67 mSv with CT.

Conclusions: Bronchography was a better investigation for diagnosing TBM and in determining opening pressures. Spiral CT is unreliable in the assessment of TBM in ventilator dependent infants. In addition, radiation doses were considerably higher with CT.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Bronchial Diseases / diagnostic imaging*
  • Bronchial Diseases / therapy
  • Bronchography / methods*
  • Continuous Positive Airway Pressure
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / diagnostic imaging
  • Infant, Premature, Diseases / therapy
  • Positive-Pressure Respiration
  • Radiation Dosage
  • Single-Blind Method
  • Tomography, X-Ray Computed / methods*
  • Tracheal Diseases / diagnostic imaging*
  • Tracheal Diseases / therapy
  • Ventilator Weaning