[Some parameters of immune response in patients infected with Toxoplasma gondii]

Pol Merkur Lekarski. 2005 Jan;18(103):85-7.
[Article in Polish]

Abstract

The immune system, its cellular and humoral response, is engaged by the host organism to fight against parasitic invasions. The group examined consisted of 52 women aged 18-42 years infected with Toxoplasma gondii. The diagnosis was established based on serologic examination. Blood for analysis was collected before antiparasitic treatment. Control group consisted of 32 healthy women aged 18-46 years. The concentrations of IgM, IgG and IgE were assayed using a set of VIDAS (bioMerieux) and the concentrations of IL-5 were assayed using a set of Quantikine human IL-5 (R&D Systems). An abnormal rise in total serum IgE can be observed in parasitosis and allergy. IL-5 is produced mainly in T-cells in response to stimulation by parasite-derived antigens and allergens The present study revealed that (in toxoplasmosis) the concentration of IgE and IL-5 contents in blood serum was higher 2-times, respectively than in healthy controls.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Biomarkers / blood
  • Female
  • Humans
  • Immunoglobulin E / blood
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Immunoglobulins / blood*
  • Interleukin-5 / blood*
  • Male
  • Middle Aged
  • Toxoplasmosis / immunology*

Substances

  • Biomarkers
  • Immunoglobulin G
  • Immunoglobulin M
  • Immunoglobulins
  • Interleukin-5
  • Immunoglobulin E