Haloxylines A and B, antifungal and cholinesterase inhibiting piperidine alkaloids from Haloxylon salicornicum

Chem Pharm Bull (Tokyo). 2005 May;53(5):570-2. doi: 10.1248/cpb.53.570.

Abstract

Haloxylines A (1) and B (2), new piperidine alkaloids, have been isolated from the chloroform soluble fraction of Haloxylon salicornicum and their structures elucidated by spectroscopic techniques including 2D-NMR. Both the compounds displayed antifungal and cholinesterase enzymes inhibitory potentials.

MeSH terms

  • Acetylcholinesterase / metabolism
  • Alkaloids / chemistry
  • Alkaloids / isolation & purification
  • Alkaloids / pharmacology*
  • Amaranthaceae*
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology*
  • Candida albicans / drug effects
  • Cholinesterase Inhibitors / chemistry
  • Cholinesterase Inhibitors / isolation & purification
  • Cholinesterase Inhibitors / pharmacology*
  • Piperidines / chemistry
  • Piperidines / isolation & purification
  • Piperidines / pharmacology*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Plant Structures

Substances

  • Alkaloids
  • Antifungal Agents
  • Cholinesterase Inhibitors
  • Piperidines
  • Plant Extracts
  • Acetylcholinesterase