The previously reported preparation of O-[(11)C]methyl-l-tyrosine ([(11)C]MT), a promising tumor imaging agent, has been now considerably simplified and automated. Main changes were the use of [(11)C]methyl iodide ([(11)C]MeI) in the reaction with l-tyrosine disodium and the use of solid phase extraction on commercially available cartridges instead of HPLC for the final purification. An injectable saline solution of [(11)C]MT was obtained within 30 min after EOB with radiochemical yield of ca. 60% (decay-corrected, based on [(11)C]MeI). Radiochemical purity was over 97%. The automated preparation was carried out using a miniature module employing manifold valves.