Ectopic gene conversions increase the G + C content of duplicated yeast and Arabidopsis genes

Mol Biol Evol. 2005 Sep;22(9):1865-8. doi: 10.1093/molbev/msi176. Epub 2005 May 25.

Abstract

Allelic recombination has previously been shown to increase the GC-content of the sequences of a wide variety of eukaryotic species. Ectopic recombination between clustered tandemly repeated genes has also been shown to increase their GC-content. Here we show that gene conversions between the dispersed genes found in the duplicated regions of the yeast and Arabidopsis genomes also increase their GC-content when these genes are more than 88% similar.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics*
  • Base Composition / genetics*
  • Evolution, Molecular
  • Gene Conversion / genetics*
  • Genes, Duplicate
  • Genes, Fungal*
  • Genes, Plant*
  • Molecular Sequence Data
  • Multigene Family
  • Open Reading Frames
  • Saccharomyces cerevisiae / genetics*
  • Selection, Genetic