Abstract
We assessed the predictive value of D-dimer (D-d) and residual venous obstruction (RVO), alone or in combination, for recurrent venous thromboembolism (VTE) over a 2-year follow-up in a cohort of 88 cancer patients after oral anticoagulant therapy (OAT) withdrawal following a first episode of proximal deep vein thrombosis of the lower limbs. RVO, determined by compression ultrasonography on the day of OAT suspension (T1), and abnormal D-d (cut-off value: 500 ng/mL), measured at T1 and 30+/-10 days afterwards, are independent risk factors for recurrent VTE in cancer patients.
Publication types
-
Letter
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Administration, Oral
-
Adult
-
Aged
-
Aged, 80 and over
-
Anticoagulants / administration & dosage*
-
Anticoagulants / adverse effects
-
Anticoagulants / therapeutic use
-
Comorbidity
-
Disease Susceptibility
-
Female
-
Fibrin Fibrinogen Degradation Products / physiology*
-
Humans
-
Male
-
Middle Aged
-
Neoplasms / blood*
-
Neoplasms / complications
-
Neoplasms / epidemiology
-
Recurrence
-
Thrombophilia / blood
-
Thrombophilia / complications
-
Thrombophilia / epidemiology
-
Thrombophlebitis / diagnostic imaging
-
Thrombophlebitis / etiology*
-
Thrombophlebitis / prevention & control
-
Ultrasonography
Substances
-
Anticoagulants
-
Fibrin Fibrinogen Degradation Products
-
fibrin fragment D