Imaging Beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic Beta cells

In Vitro Cell Dev Biol Anim. 2005 Jan-Feb;41(1-2):7-11. doi: 10.1290/0412080.1.

Abstract

We present a convenient method for monitoring pancreatic beta cell development in real-time, through in vitro culture of embryonic pancreatic explants from transgenic mice with a genetic tag for insulin-producing beta cells.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Culture Techniques / methods
  • Green Fluorescent Proteins / metabolism*
  • Islets of Langerhans / cytology*
  • Islets of Langerhans / embryology*
  • Mice
  • Mice, Transgenic
  • Microscopy, Fluorescence
  • Transgenes / genetics

Substances

  • Green Fluorescent Proteins