Bilateral benign lymphoid hyperplasia of the conjunctiva in a paediatric patient

Clin Exp Ophthalmol. 2005 Jun;33(3):285-7. doi: 10.1111/j.1442-9071.2005.01002.x.

Abstract

A 14-year-old boy presented with a 6-month history of bilateral slowly enlarging conjunctival lesions. There was no associated ocular or systemic symptomatology. Examination revealed bilateral salmon-coloured nodular lesions of the bulbar conjunctiva. The remainder of his ophthalmic and general examinations were normal. Extensive investigation excluded regional or systemic involvement. Excision biopsy of the lesions showed a predominantly mature B lymphocyte infiltrate with immunohistochemistry and flow cytometry consistent with reactive lymphoid hyperplasia. Polymerase chain reaction testing for Epstein-Barr virus was negative. At 2 years follow-up, the patient remained healthy and there was no evidence of recurrence. Benign lymphoid hyperplasia of the conjunctiva with bilateral involvement is extremely rare in children. Only a few case reports have been documented in the literature.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • B-Lymphocytes / pathology
  • Biopsy
  • Conjunctival Diseases / pathology*
  • Conjunctival Diseases / surgery
  • Flow Cytometry
  • Functional Laterality
  • Humans
  • Immunohistochemistry
  • Male
  • Polymerase Chain Reaction
  • Pseudolymphoma / pathology*
  • Pseudolymphoma / surgery