Elevated plasma vascular endothelial growth factor levels in 2 patients with hemangioendothelioma

Michal A Miller; Anthony D Sandler

doi:10.1016/j.jpedsurg.2005.02.014

Elevated plasma vascular endothelial growth factor levels in 2 patients with hemangioendothelioma

J Pediatr Surg. 2005 May;40(5):e17-9. doi: 10.1016/j.jpedsurg.2005.02.014.

Authors

Michal A Miller¹, Anthony D Sandler

Affiliation

¹ Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

PMID: 15937808
DOI: 10.1016/j.jpedsurg.2005.02.014

Abstract

Two patients with hemangioendothelioma and elevated plasma vascular endothelial growth factor (VEGF) levels are presented. A reduction in the plasma VEGF level after therapeutic intervention correlated with a successful clinical response. Conversely, a stable plasma VEGF level correlated with therapeutic failure.

Publication types

Case Reports

MeSH terms

Biomarkers, Tumor / blood*
Hemangioendothelioma / blood*
Hemangioendothelioma / congenital
Hemangioendothelioma / surgery
Hepatectomy
Hip Contracture / etiology
Hip Contracture / pathology
Humans
Infant
Liver Neoplasms / blood*
Liver Neoplasms / congenital
Liver Neoplasms / surgery
Magnetic Resonance Imaging
Male
Neoplasm Proteins / blood*
Neoplasm Recurrence, Local / drug therapy
Prednisolone / therapeutic use
Soft Tissue Neoplasms / blood*
Soft Tissue Neoplasms / drug therapy
Soft Tissue Neoplasms / surgery
Subcutaneous Tissue
Vascular Endothelial Growth Factor A / blood*

Substances

Biomarkers, Tumor
Neoplasm Proteins
VEGFA protein, human
Vascular Endothelial Growth Factor A
Prednisolone