Human tandem repeat sequences in forensic DNA typing

Keiji Tamaki; Alec J Jeffreys

doi:10.1016/j.legalmed.2005.02.002

Human tandem repeat sequences in forensic DNA typing

Leg Med (Tokyo). 2005 Jul;7(4):244-50. doi: 10.1016/j.legalmed.2005.02.002.

Authors

Keiji Tamaki¹, Alec J Jeffreys

Affiliation

¹ Department of Legal Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan. [email protected]

PMID: 15939656
DOI: 10.1016/j.legalmed.2005.02.002

Abstract

It has been 20 years since the first development of DNA fingerprinting and the start of forensic DNA typing. Ever since, human tandem repeat DNA sequences have been the main targets for forensic DNA analysis. These repeat sequences are classified into minisatellites (or VNTRs) and microsatellites (or STRs). In this brief review, we discuss the historical and current forensic applications of such tandem repeats.

Publication types

Review

MeSH terms

DNA Fingerprinting / methods*
Gene Frequency
Humans
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Tandem Repeat Sequences*