Abstract
Plasmodium falciparum msp-1 and msp-2 genes were quantified by fragment analysis in matched placental, peripheral, and cord blood samples. In the three compartments, the multiplicity of infection values were similar, and parasite populations only partially overlapped, as reported. However, identical alleles represented 80 to 95% of the overall parasite populations of each compartment, demonstrating much more homogenous parasite populations than previously thought.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Alleles*
-
Animals
-
Antigens, Protozoan / genetics
-
Blood / parasitology*
-
Female
-
Fetal Blood / parasitology*
-
Humans
-
Infant, Newborn
-
Malaria, Falciparum / parasitology*
-
Merozoite Surface Protein 1 / genetics
-
Placenta / parasitology*
-
Plasmodium falciparum / genetics*
-
Plasmodium falciparum / isolation & purification
-
Pregnancy
-
Pregnancy Complications, Parasitic / parasitology
-
Protozoan Proteins / genetics
Substances
-
Antigens, Protozoan
-
Merozoite Surface Protein 1
-
Protozoan Proteins
-
merozoite surface protein 2, Plasmodium