1,3-Dimethyllumazine derivatives from Limnatis nilotica

Gerard Voerman; Silvia Cavalli; Gijsbert A van der Marel; Wolfgang Pfleiderer; Jacques H van Boom; Dmitri V Filippov

doi:10.1021/np049617a

1,3-Dimethyllumazine derivatives from Limnatis nilotica

J Nat Prod. 2005 Jun;68(6):938-41. doi: 10.1021/np049617a.

Authors

Gerard Voerman¹, Silvia Cavalli, Gijsbert A van der Marel, Wolfgang Pfleiderer, Jacques H van Boom, Dmitri V Filippov

Affiliation

¹ Leiden Institute of Chemistry, Leiden University, The Netherlands.

PMID: 15974624
DOI: 10.1021/np049617a

Abstract

Two previously unknown lumazine derivatives, 1 and 2, have been isolated from the parasitic freshwater leech Limnatis nilotica. The structures of the compounds have been elucidated by NMR and unambiguously corroborated by chemical synthesis.

MeSH terms

Animals
Leeches / chemistry*
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Pteridines / chemistry*
Pteridines / isolation & purification*

Substances

Pteridines
lumazine