No adverse effects of adjuvant chemotherapy on hippocampal volume in Japanese breast cancer survivors

Breast Cancer Res Treat. 2005 Jul;92(1):81-4. doi: 10.1007/s10549-005-1412-6.

Abstract

We investigated the adverse effects of adjuvant chemotherapy on the hippocampus in Japanese breast cancer survivors with (n=44) and without (n=31) adjuvant chemotherapy. There were no significant differences in hippocampal volume (magnetic resonance imaging) or additionally in memory function (Wechsler Memory Scale-Revised) between the two groups.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / surgery
  • Female
  • Hippocampus / drug effects*
  • Humans
  • Japan
  • Magnetic Resonance Imaging
  • Mastectomy
  • Memory Disorders / chemically induced*
  • Memory Disorders / diagnosis
  • Middle Aged
  • Neuropsychological Tests
  • Organ Size / drug effects
  • Survivors

Substances

  • Antineoplastic Agents