Options for mechanical circulatory support for the treatment of end-stage heart failure in children are limited. Ventricular assist devices (VADs), which have revolutionized cardiac care in adults, remain largely unavailable for pediatric applications. The PediPump is a new rotary dynamic VAD designed to provide support for the entire range of patient sizes encountered in pediatrics. Despite being much smaller than currently available VADs, which makes it suitable for even newborn circulatory support, the PediPump demonstrates excellent hemodynamic performance.