Long-term outcome of meningococcal sepsis-associated acute renal failure

Pediatr Crit Care Med. 2005 Jul;6(4):477-9. doi: 10.1097/01.PCC.0000163285.74452.23.

Abstract

Setting: Twenty-one of 209 children admitted to the intensive care unit with meningococcal septicemia developed oliguric acute renal failure necessitating renal replacement therapy.

Patients: Twelve survivors underwent renal assessment at a median of 4.2 yrs postpresentation.

Result: Two had abnormal glomerular filtration rate, proteinuria, and hypertension; one had isolated proteinuria; and one had an isolated renal parenchymal defect on DMSA scan.

Conclusion: Long-term follow-up of this population is recommended.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Kidney Injury / microbiology
  • Acute Kidney Injury / physiopathology*
  • Acute Kidney Injury / therapy
  • Adolescent
  • Adult
  • Bacteremia / complications*
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Kidney Diseases / epidemiology*
  • Kidney Diseases / etiology
  • Kidney Function Tests
  • Male
  • Meningococcal Infections / complications*
  • Renal Replacement Therapy
  • Survivors*
  • United Kingdom / epidemiology