P2Y1 receptors inhibit both strength and plasticity of glutamatergic synaptic neurotransmission in the rat prefrontal cortex

Synapse. 2005 Sep 15;57(4):235-8. doi: 10.1002/syn.20177.

Authors

Segundo J Guzman¹, Zoltan Gerevich, Jan G Hengstler, Peter Illes, Werner Kleemann

Affiliation

¹ Rudolf-Boehm-Institute of Pharmacology and Toxicology, University of Leipzig, D-04107 Leipzig, Germany.

PMID: 15986393
DOI: 10.1002/syn.20177

No abstract available

MeSH terms

Animals
Electric Stimulation
Excitatory Postsynaptic Potentials / physiology*
Glutamine / metabolism*
Male
Neuronal Plasticity / physiology*
Organ Culture Techniques
Patch-Clamp Techniques
Prefrontal Cortex / physiology*
Purinergic P2 Receptor Agonists
Purinergic P2 Receptor Antagonists
Pyramidal Cells / metabolism
Rats
Receptors, Purinergic P2 / metabolism*
Receptors, Purinergic P2Y1
Synaptic Transmission / physiology*

Substances

P2ry1 protein, rat
Purinergic P2 Receptor Agonists
Purinergic P2 Receptor Antagonists
Receptors, Purinergic P2
Receptors, Purinergic P2Y1
Glutamine