New highly nucleophilic and practically accessible chlorocarbenoids for carbonyl olefination

J Org Chem. 2005 Jul 8;70(14):5745-7. doi: 10.1021/jo050455c.

Abstract

[reaction: see text] Direct oxidative addition of CHCl3 to the Mg-TiCl4 bimetallic species resulted in the generation of a highly nucleophilic and practically convenient chloromethylenetitanium complex, which efficiently effected condensation even with enolizable or inert carbonyl compounds, such as sterically congested ketones, to provide vinyl chloride compounds.