Electroconvulsive therapy for depression in a Parkinson's disease patient with bilateral subthalamic nucleus deep brain stimulators

Parkinsonism Relat Disord. 2005 Sep;11(6):403-6. doi: 10.1016/j.parkreldis.2005.04.005.

Abstract

We report a patient with advanced Parkinson's disease (PD) who developed a recurrence of major depression with psychotic features after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery. Electroconvulsive therapy (ECT) dramatically improved the depression without shifting electrode position or damaging the DBS hardware. This case suggests that ECT can be a safe and effective option for severe depression in PD patients treated with STN DBS.

Publication types

  • Case Reports

MeSH terms

  • Antiparkinson Agents / therapeutic use
  • Antipsychotic Agents / therapeutic use
  • Deep Brain Stimulation*
  • Depressive Disorder, Major / etiology*
  • Depressive Disorder, Major / therapy*
  • Dibenzothiazepines / therapeutic use
  • Electroconvulsive Therapy*
  • Female
  • Humans
  • Levodopa / therapeutic use
  • Magnetic Resonance Imaging
  • Middle Aged
  • Parkinson Disease / complications*
  • Parkinson Disease / therapy
  • Quetiapine Fumarate
  • Subthalamic Nucleus / physiology*

Substances

  • Antiparkinson Agents
  • Antipsychotic Agents
  • Dibenzothiazepines
  • Quetiapine Fumarate
  • Levodopa