Abstract
Leptospirosis is an acute generalized infectious disease, caused by spirochaetes, Leptospira interrogans. The severity of the disease ranges from an asymptomatic subclinical course to a fatal outcome. The three cases presented here were diagnosed serologically and had thrombocytopenia and acute renal failure as complication of anicteric leptospirosis. Our first case admitted with clinical presentation of pneumonia but clinical progress and laboratory findings made us to consider leptospirosis. The other two cases presented with aseptic meningitis were diagnosed as anicteric leptospirosis by the serological test results. One of the cases had fatal outcome but could not be strictly correlated with leptospirosis.
MeSH terms
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Acute Kidney Injury / etiology*
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Acyclovir / administration & dosage
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Adult
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Aged
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Agglutination Tests
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Ampicillin / administration & dosage
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Anti-Bacterial Agents / administration & dosage
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Antibodies, Bacterial / blood
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Ceftriaxone / administration & dosage
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Clarithromycin / administration & dosage
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Doxycycline / administration & dosage
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Drug Therapy, Combination
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Enoxaparin / administration & dosage
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Fatal Outcome
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Female
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Humans
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Leptospira interrogans / immunology
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Leptospira interrogans / isolation & purification*
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Leptospirosis / complications*
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Leptospirosis / diagnosis
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Leptospirosis / drug therapy*
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Leptospirosis / microbiology
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Male
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Middle Aged
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Thrombocytopenia / etiology*
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Turkey
Substances
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Anti-Bacterial Agents
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Antibodies, Bacterial
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Enoxaparin
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Ceftriaxone
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Ampicillin
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Clarithromycin
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Doxycycline
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Acyclovir