[Gene targeting approaches for diabetes research]

Nihon Rinsho. 2005 Jun:63 Suppl 6:111-24.
[Article in Japanese]
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Diabetes Mellitus, Type 2 / etiology*
  • Disease Models, Animal
  • Endothelium, Vascular / pathology
  • Endothelium, Vascular / physiopathology
  • Gene Expression Regulation
  • Gene Targeting / methods*
  • Genetic Engineering / methods
  • Humans
  • Insulin / metabolism
  • Insulin Receptor Substrate Proteins
  • Insulin Resistance
  • Insulin Secretion
  • Intracellular Signaling Peptides and Proteins
  • Mice
  • Mice, Knockout
  • Mice, Transgenic
  • Phosphoproteins / genetics
  • Receptor, Insulin / genetics

Substances

  • IRS1 protein, human
  • IRS2 protein, human
  • Insulin
  • Insulin Receptor Substrate Proteins
  • Intracellular Signaling Peptides and Proteins
  • Irs1 protein, mouse
  • Irs2 protein, mouse
  • Phosphoproteins
  • Receptor, Insulin