Abstract
We report the first strain of glycopeptide-resistant Enterococcus faecium from Europe that contains a vanD allele isolated from blood cultures of an immunocompromised patient hospitalized in a French university hospital. Based on phenotypic results, PCR sequencing, pulsed-field gel electrophoresis, and Southern blotting, the isolate was assigned to E. faecium with a chromosomally located VanD allele most closely related to the VanD1 allele.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Anti-Bacterial Agents / pharmacology*
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Bacterial Proteins / genetics*
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Drug Resistance, Bacterial*
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Electrophoresis, Gel, Pulsed-Field
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Enterococcus faecium / classification
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Enterococcus faecium / drug effects
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Enterococcus faecium / genetics
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Enterococcus faecium / isolation & purification*
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Europe
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Fatal Outcome
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Glycopeptides*
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Gram-Positive Bacterial Infections / microbiology*
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Humans
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Molecular Sequence Data
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Peptide Synthases / genetics*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Glycopeptides
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Peptide Synthases
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VanD protein, Enterococcus faecium