Non-mediastinal grey zone lymphomas and report from the workshop

Eur J Haematol Suppl. 2005 Jul:(66):42-4. doi: 10.1111/j.1600-0609.2005.00453.x.

Abstract

Grey zone lymphomas represent borderline lesions between classical Hodgkin lymphoma (cHL) and other morphologically and immunophenotypically related diseases and entities like nodular lymphocyte predominant HL, T-cell rich B-cell lymphoma, ALK-negative anaplastic large cell lymphoma (ALCL), diffuse large B cell lymphoma (DLBCL) anaplastic variant and primary mediastinal LBCL. The sharp definition of morphological, immunophenotypical and molecular features of the "text-book cases" of each disease and the comparison with grey zone cases has reduced most of the latter cases. Two reports in this workshop dealt with the problematic non-mediastinal grey zone lymphomas, one with a cHL of T cell-type presenting in the skin as a ALK-negative ALCL and the other with the grey zone between cHL of B-cell type and ALK-negative ALCL.

MeSH terms

  • Education
  • Hodgkin Disease / classification*
  • Hodgkin Disease / pathology
  • Hodgkin Disease / physiopathology
  • Humans
  • Lymphoma, Non-Hodgkin / classification*
  • Lymphoma, Non-Hodgkin / pathology
  • Lymphoma, Non-Hodgkin / physiopathology