Nerve conduction study, electromyography and somatosensory evoked potentials in non-Friedreich early onset cerebellar ataxia. A comparative study with Friedreich's ataxia and late onset cerebellar ataxia

Electromyogr Clin Neurophysiol. 1992 Apr-May;32(4-5):207-14.

Abstract

Electrophysiological findings in 14 patients with non-Friedreich early onset cerebellar ataxia are reported. Nerve conduction studies showed reduction of sensory action potential amplitudes in 7 cases associated in 3 with a decrease of sensory conduction velocities. Six subjects also exhibited a chronic neurogenic pattern to standard needle electromyography. Motor conduction velocities were normal in all cases; only two cases showed an increase in distal motor latencies. Short-latency somatosensory evoked potentials following median nerve stimulation revealed a prolonged central conduction time (N13-N20 interpeak latency) in 7 cases, compatible with supraspinal damage of the somatosensory pathways. These electrophysiological data are compared with those obtained in two reference groups of patients, respectively affected by Friedreich's ataxia and olivo-ponto-cerebellar atrophy.

Publication types

  • Comparative Study

MeSH terms

  • Action Potentials / physiology
  • Adolescent
  • Adult
  • Cerebellar Ataxia / physiopathology*
  • Child
  • Electromyography
  • Evoked Potentials, Somatosensory / physiology*
  • Female
  • Friedreich Ataxia / physiopathology*
  • Humans
  • Male
  • Neural Conduction / physiology*
  • Time Factors