Mild and efficient removal of hydroxyethyl unit from 2-hydroxyethyl ether derivatives leading to alcohols

Hiromichi Fujioka; Yusuke Ohba; Hideki Hirose; Kenichi Murai; Yasuyuki Kita

doi:10.1021/ol051135i

Mild and efficient removal of hydroxyethyl unit from 2-hydroxyethyl ether derivatives leading to alcohols

Org Lett. 2005 Jul 21;7(15):3303-6. doi: 10.1021/ol051135i.

Authors

Hiromichi Fujioka¹, Yusuke Ohba, Hideki Hirose, Kenichi Murai, Yasuyuki Kita

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan. [email protected]

PMID: 16018646
DOI: 10.1021/ol051135i

Abstract

[reaction: see text]. CAN is a good reagent for the transformation of 2-hydroxyethyl ether units to alcohols. Significantly, many functional groups can tolerate the reaction conditions, although they do not survive under many previously reported removal conditions. The reaction mechanism is clarified.