Clear cell sarcoma: a dilemma on pathological staging and clinical management

Pediatr Hematol Oncol. 2005 Apr-May;22(3):257-61. doi: 10.1080/08880010590921685.

Abstract

Clear cell sarcoma of the kidney (CCSK) has been classified as high risk tumour in the previous UK and international Wilms tumor studies. The current Society of Paediatric Oncology (SIOP) trial, UK version, advocates chemotherapy including doxorubicin prior to nephrectomy. Pathological staging and histology of the resected tumor are then applied to determine the extent and intensity of the postoperative therapy. We describe an unusual case with a trilobed tumor and debate the appropriate postoperative management.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Doxorubicin / therapeutic use
  • Humans
  • Infant
  • Kidney Neoplasms / drug therapy
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Male
  • Neoplasm Staging
  • Nephrectomy / methods
  • Postoperative Care / methods
  • Sarcoma, Clear Cell / drug therapy
  • Sarcoma, Clear Cell / pathology*
  • Sarcoma, Clear Cell / surgery

Substances

  • Doxorubicin