Abstract
The isolation and structural elucidation of westiellamide [1] from the terrestrial blue-green alga Westiellopsis prolifica is described. This moderately cytotoxic cyclic peptide appears to be identical with a bistratamide-type marine natural product from the aplouso-branch ascidian Lissoclinum bistratum.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology
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Cyanobacteria / chemistry*
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Drug Screening Assays, Antitumor
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Humans
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Magnetic Resonance Spectroscopy
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Molecular Sequence Data
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Molecular Structure
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Peptides, Cyclic / chemistry
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Peptides, Cyclic / isolation & purification*
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Tumor Cells, Cultured / drug effects
Substances
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Antineoplastic Agents
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Peptides, Cyclic
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westiellamide