[Tubulointerstitial nephritis with uveitis (TINU) syndrome]

Wiad Lek. 2005:58 Suppl 1:98-101.
[Article in Polish]

Abstract

Authors present an 11-year old girl with non-specific clinical symptoms with increase of inflammatory indices and acute non-oliguric renal failure: creatinine clearance - 55 ml/min/1.73 m2. An anterior uveitis was observed after 7 weeks of illness. Diagnosis of tubulointerstitial nephritis with uveitis (TINU) was confirmed by interstitial infiltrate (lymphocytes, neutrophils, eosinophils) and interstitial fibrosis in renal biopsy. Steroid therapy was given for 7 months. Uveitis without kidney involvement relapsed 1 month after discontinuation of steroid therapy. The full recovery of uveitis was achieved after the treatment with topical steroids. After 3 years, the illness remains still in remission.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Kidney Injury / etiology
  • Adrenal Cortex Hormones / administration & dosage
  • Child
  • Female
  • Humans
  • Nephritis, Interstitial* / complications
  • Nephritis, Interstitial* / diagnosis
  • Nephritis, Interstitial* / therapy
  • Syndrome
  • Time Factors
  • Treatment Outcome
  • Uveitis, Anterior* / complications
  • Uveitis, Anterior* / diagnosis
  • Uveitis, Anterior* / therapy

Substances

  • Adrenal Cortex Hormones