Is total laparoscopic surgery for endometrial carcinoma at risk of local recurrence? A long-term survival

Anticancer Res. 2005 May-Jun;25(3c):2423-8.

Abstract

Background: Loco-regional recurrences after laparotomic surgery for early endometrial carcinoma have an incidence of 3-8%. This study examined the pattern of recurrences and survival after full laparoscopic hysterectomy.

Patients and methods: Between January 1997 and December 2002, 113 consecutive patients with pre-operative Stage I endometrial cancer, self-referred to two different surgical teams, were treated by the laparoscopic approach by one team and by the laparotomic approach by the other team.

Results: Nineteen patients were treated by total laparoscopic hysterectomy (TLH) by the endoscopic group, and 94 were treated by total abdominal hysterectomy (TAH) by the oncologic group. Sixteen patients (84.2%) in the laparoscopic group and 79 patients (84.0%) in the laparotomic group had Stage I disease. The mean age and mean weight did not differ in the two groups. With a mean follow-up of 52.2 months for the TLH group and 43.6 months for the TAH group, one recurrence (5.3%) was observed in the former group and 9 recurrences (10.6%) in the latter group. No significative differences were observed for disease-free survival and overall survival.

Conclusion: Total laparoscopic hysterectomy does not increase the risk of local recurrence and does not affect survival for patients with early stage endometrial carcinoma.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Disease-Free Survival
  • Endometrial Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Hysterectomy / adverse effects
  • Hysterectomy / methods
  • Laparoscopy / adverse effects
  • Laparoscopy / methods
  • Lymph Node Excision / adverse effects
  • Lymph Node Excision / methods
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Risk Factors
  • Survival Rate
  • Treatment Outcome