Neural pattern dynamics in an oscillator model of the thalamo-reticular system

J Physiol Paris. 2006 Jan;99(1):66-71. doi: 10.1016/j.jphysparis.2005.06.008. Epub 2005 Aug 8.

Abstract

One of development issues for information processing with synchronous oscillations in the brain is how new information is coded and how a comparison with already existing information is performed. In the present work we study a simple neural network model of the thalamo-reticular system based on the Wilson-Cowan model of neuronal oscillatory behavior. Our results show that both cortical control over the thalamus and external sensory input are essential in coordinating and generating spatio-temporal patterns of synchronous activity. A main finding of the numerical simulations is that the network connectivity and the intrinsic oscillatory properties of the neurons result in distinct collective behaviors within the network. By varying the connectivity schemes comparable with lesionated or damaged brain regions our results are in good agreement with in vivo experimental results. Suppressing the sensory input results in temporal oscillatory activity in the beta and gamma range and a strong spatial dependence of the network activity.

MeSH terms

  • Algorithms
  • Cerebral Cortex / physiology
  • Feedback / physiology
  • Humans
  • Memory, Short-Term / physiology
  • Models, Neurological
  • Models, Statistical
  • Nerve Net / physiology*
  • Reticular Formation / physiology*
  • Thalamus / physiology*