Abstract
The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Bacteriophage lambda / chemistry
-
Bacteriophage lambda / genetics
-
DNA, Viral / chemistry*
-
DNA, Viral / immunology
-
Nanotechnology / methods
-
Nanotubes / chemistry*
-
Silicon Dioxide / chemistry
Substances
-
DNA, Viral
-
Silicon Dioxide