Results of post-operative or exclusive radiotherapy in grade I and grade II cerebellar astrocytoma patients

Radiother Oncol. 1992 Apr;23(4):245-8. doi: 10.1016/s0167-8140(92)80129-7.

Abstract

43 Patients with the diagnosis of cerebellar astrocytoma were post-operatively treated, between 1 January 1976 and 31 December 1985. Their age ranged between 2 and 51 years with a median of 13. There were 22 males and 21 females. The tumours were reported as grade I in 18, and grade II in 25 patients. The primary surgical intervention was in the form of biopsy in 3, subtotal excision in 24 and macroscopic total excision in 16. All patients were treated with cobalt-60 teletherapy unit, to a total tumour dose of 4500-5500 cGy in 6-7 weeks. The obtained 5 and 10 year actuarial survival rates are 78% and 78%. Our study gives the impression that, age, sex and tumour grade are not determining factors in survival and post-operative radiotherapy improves prognosis in cases treated by subtotal excision while it remains unnecessary in those who had undergone total surgical removal.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Astrocytoma / radiotherapy*
  • Astrocytoma / surgery*
  • Cerebellar Neoplasms / radiotherapy*
  • Cerebellar Neoplasms / surgery*
  • Child
  • Child, Preschool
  • Cobalt Radioisotopes
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Care
  • Prognosis
  • Radiotherapy Dosage
  • Survival Rate

Substances

  • Cobalt Radioisotopes