Palladium-catalyzed one-pot synthesis of highly substituted furans by a three-component annulation reaction

Xin-hua Duan; Xue-yuan Liu; Li-na Guo; Meng-chun Liao; Wei-Min Liu; Yong-min Liang

doi:10.1021/jo050908d

Palladium-catalyzed one-pot synthesis of highly substituted furans by a three-component annulation reaction

J Org Chem. 2005 Aug 19;70(17):6980-3. doi: 10.1021/jo050908d.

Authors

Xin-hua Duan¹, Xue-yuan Liu, Li-na Guo, Meng-chun Liao, Wei-Min Liu, Yong-min Liang

Affiliation

¹ State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P.R. China.

PMID: 16095331
DOI: 10.1021/jo050908d

Abstract

A new three-component cyclization-coupling reaction catalyzed by palladium was developed, producing polysubstituted furans in good yields from readily available substrates. The reaction conditions and the scope of the process were examined, and a possible mechanism is proposed.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Catalysis
Furans / chemical synthesis*
Magnetic Resonance Spectroscopy
Palladium / chemistry*
Spectrometry, Mass, Electrospray Ionization
Spectrophotometry, Infrared

Substances

Furans
Palladium